HTML 5 and CSS3
These are the building blocks of the web, and will continue to be for the foreseeable future. Any website you visit has been built using HTML and CSS - even Google! I’ve been writing HTML and CSS for ages and know my way around both of them very well. I code everything by hand, which means no bloated, ‘buggy’ code. It also ensures that the code complies with web standards, is accessible, and renders quickly and properly in all popular web browsers.
JavaScript
I am a fan of jQuery.